If you’re starting your weight loss journey with Mounjaro or considering it as a treatment option, you may have seen references to a Mounjaro dosage chart. But what exactly does that mean? How does the dosage change over time? And how can you make sure you’re following it correctly?
In this post, we’ll walk you through the step-by-step dosage schedule, explain what to expect at each stage, and offer tips to make the experience easier and more effective.
What Is Mounjaro?
Mounjaro (tirzepatide) is a once-weekly injection originally developed for managing type 2 diabetes. More recently, it’s become widely used to support medical weight loss—especially for people with a high BMI or weight-related health concerns.
It works by mimicking the effects of two hormones (GLP-1 and GIP) that control blood sugar levels, slow digestion, and help you feel full for longer. The result? A noticeable reduction in appetite and, over time, significant weight loss when used alongside healthy lifestyle changes.
Why the Dosage Increases Over Time
Mounjaro isn’t something you start at full strength from day one. Like many hormone-based medications, your body needs time to adjust. That’s why the treatment begins with a low starting dose and increases gradually over the course of several weeks.
This gradual approach helps:
- Minimise side effects such as nausea, fatigue, or upset stomach
- Allow your body to build tolerance to the medication
- Ensure long-term success by setting a steady pace for weight loss
We carefully monitor your progress and adjust the plan based on how well your body responds.
Mounjaro Dosage Escalation Chart
Below is a typical dosage schedule, showing how the strength of your injection increases every four weeks:
Treatment Weeks Dosage (mg/week)
Weeks 1-4 2.5 mg
Weeks 5-8 5.0 mg
Weeks 9-12 7.5 mg
Week 13+ 10.0 mg and beyond
After week 13, depending on your progress and tolerance, the dose may increase further to 12.5 mg or 15 mg, which is the highest approved level.
Please note: Not everyone needs to move up to the maximum dose. Some people achieve excellent results at 7.5 mg or 10 mg, and we’ll always personalise your plan.
What to Expect at Each Stage
Everyone’s experience with Mounjaro is different, but here’s a general idea of how each phase might feel:
Weeks 1–4: Getting Started (2.5 mg)
This is your introductory phase. Most people notice a reduced appetite and fewer cravings. Weight loss is usually mild, but it’s not the main goal just yet—it’s all about preparing your body.
Common sensations:
- Feeling full faster
- Slight nausea or tiredness
- No major weight shifts (yet)
Weeks 5–8: Stepping Up (5 mg)
You may feel the effects more clearly now. The reduced hunger becomes more consistent, and you may start to lose weight steadily.
Common sensations:
- Easier to eat smaller meals
- Occasional digestive discomfort
- Early signs of fat loss
Weeks 9–12: Building Momentum (7.5 mg)
Your appetite may shrink even further, and weight loss often picks up pace. This is when you may start noticing real changes in how your clothes fit or how you feel day to day.
Week 13+: Therapeutic Dose (10 mg and above)
By now, Mounjaro is doing its best work. You’re likely to see more visible progress—alongside positive lifestyle changes like increased energy, healthier eating habits, and more stable blood sugar.
Can You Still Eat Normally?
Yes, but your eating habits will likely change—naturally. Many people find they’re less hungry and more in control of their food choices once the medication kicks in.
We recommend:
- Eating slowly and stopping when you feel full
- Focusing on whole foods (lean protein, veg, whole grains)
- Avoiding overly processed, high-sugar meals
- Staying well hydrated, especially after your injection
- Keeping a food diary to understand your new habits
This isn’t about restricting your diet—it’s about learning what your body needs and responding to hunger cues more effectively.
Are There Side Effects?
Like any medication, Mounjaro can cause side effects, especially in the early weeks. These are usually mild and temporary:
Most common:
- Nausea
- Bloating or indigestion
- Constipation or diarrhoea
- Fatigue
To reduce side effects:
- Take your injection on the same day each week
- Don’t skip meals (even small ones)
- Avoid greasy, rich foods during the first few days after your injection
- Stay in regular contact with us so we can adjust if needed
If side effects persist beyond a few weeks, we may recommend pausing your dosage increase or trying a different strategy.
How We Support You at Every Stage
Starting Mounjaro isn’t just about receiving a prescription—it’s about having the right support system in place. At Manchester Weight Loss Clinic, we tailor your treatment to your needs, check in with you regularly, and provide advice that’s easy to follow in real life.
We’re operated by Heald Green Pharmacy, and our team has the experience and medical knowledge to guide you through your entire journey. We’ll:
- Help you understand your dosage schedule
- Track your progress and adjust your plan if needed
- Offer realistic nutritional and lifestyle tips
- Be here to answer any questions or concerns you have
Ready To Start Mounjaro?
If you’ve been looking for a clear, trustworthy guide to the Mounjaro dosage chart, we hope this has helped. Understanding how the treatment works—and what to expect along the way—is the first step toward real, long-term change.
At Manchester Weight Loss Clinic, we’re here to support you every step of the way. Whether you’re just getting started or you’ve tried other options in the past, our team will help you find a path that works for you. Get in touch today or book an appointment and see how we can help you on your weight loss journey.
This blog was written on behalf of Manchester Weight Loss Clinic by Pharmacy Mentor.