Losing weight isn’t easy—especially when juggling work, home life, and everything in between. That’s why more and more people are asking: what is the best injection for weight loss at home?
With new options available and growing awareness around medical weight management, it’s now possible to access safe and effective treatment without having to attend weekly clinic appointments or drastic weight loss programmes.
At Manchester Weight Loss Clinic, we’re on hand to explain what injections are available, how they work, and which one might be right for your at-home weight loss journey.
Why Use Weight Loss Injections at Home?
Weight loss injections are prescription medications designed to help regulate appetite, stabilise blood sugar levels, and support long-term fat reduction. When used alongside lifestyle changes like diet and exercise, they can make a noticeable difference.
Administering them at home means you can follow your treatment in a way that’s flexible, discreet, and easy to manage—without having to visit a clinic every week.
Most are once-daily or once-weekly injections, taken subcutaneously (just under the skin), usually in the stomach, thigh, or upper arm.

The Two Main Injections Used in the UK
If you're wondering what is the best injection for weight loss at home, there are currently two standout options available on prescription in the UK:
Saxenda (Liraglutide)
- How often? Daily injection
- How it works: Mimics a hormone called GLP-1, which helps you feel full and slows digestion
- Who it’s for: Adults with a BMI over 30, or over 27 with a weight-related condition
- Home suitability: Comes in a pre-filled pen, easy to use at home after guidance
Saxenda is well-established and has helped many people lose between 5–10% of their body weight over time. It requires daily use, so it’s ideal for those who are consistent with routines.
Mounjaro (Tirzepatide)
- How often? Weekly injection
- How it works: Targets both GLP-1 and GIP receptors to control appetite and blood sugar
- Who it’s for: Initially developed for type 2 diabetes but now widely prescribed for weight loss
- Home suitability: Weekly pen injection with a clear dosage escalation schedule
Mounjaro is one of the most exciting developments in medical weight loss, with clinical trials showing up to 15–20% weight loss in some patients. It’s a strong contender for the best weight loss injection to use at home, especially for those who prefer less frequent dosing.
Choosing the Right Injection for You
Both Saxenda and Mounjaro are proven, medically approved options—but which one is better depends on your needs, preferences, and health background.
Consider the following:
- How often can you realistically inject? (Daily vs. weekly)
- Do you have other conditions like type 2 diabetes?
- Are you comfortable managing your treatment from home?
- Do you want rapid results, or steady progress over time?
- What support do you have from your provider or clinic?
The good news is that both options come with clear instructions, support from your prescriber, and regular reviews to help you stay on track.
Are At-Home Injections Safe?
Yes—when prescribed and monitored by a licensed professional, weight loss injections are safe to use at home. Most people find them simple to use after an initial demo or video tutorial.
Side effects are possible, especially in the first few weeks. These include:
- Nausea
- Constipation or diarrhoea
- Fatigue
- Mild headaches
We always recommend staying in regular contact with your clinic and reporting anything unusual. Most side effects settle after your body adjusts to the medication.
What Else Can You Do to Boost Results?
Using a weight loss injection at home is a fantastic tool—but it’s not a magic fix. The best results come when injections are used alongside:
- Balanced, portion-controlled meals
- Regular physical activity (even just walking daily)
- Adequate sleep and hydration
- Stress management (as this impacts hunger and metabolism)
Our patients often find that once appetite is controlled, it becomes much easier to focus on making healthy choices consistently.

Ready to Try Weight Loss Injections at Home?
Still wondering what is the best injection for weight loss at home? The answer depends on your personal goals and medical history—but with the right support, both Saxenda and Mounjaro can offer real results.
At Manchester Weight Loss Clinic, we offer medically supervised weight loss injections that you can use safely and confidently from the comfort of your own home. From your first consultation to ongoing support, we’re here to make the process as smooth and effective as possible.
Feel free to get in touch with us today to see how we can help and support you on your weight loss journey.
This blog was written on behalf of Manchester Weight Loss Clinic by Pharmacy Mentor.
