At Manchester Weight Loss Clinic, we understand that starting a new treatment like Mounjaro can be an exciting step towards better health and confidence. Mounjaro (tirzepatide) has helped many people achieve significant weight loss by reducing appetite, improving blood sugar control, and supporting healthier eating habits. However, while Mounjaro is highly effective for many, it does not work for everyone.
If you’re taking Mounjaro and not seeing the results you expected, you’re not alone. There are several reasons why your progress may be slower than anticipated, and there are alternative weight loss injections and treatments that may be better suited to your individual needs.
Why Mounjaro May Not Be Working for You
Although clinical studies have shown impressive results, Mounjaro’s effectiveness can vary from person to person. Here are some possible reasons why you may not be losing weight:
Your Body's Response is Different
Every person’s metabolism and hormonal balance are unique. While Mounjaro works by targeting GLP-1 and GIP receptors to regulate appetite and blood sugar, some people’s bodies may not respond as strongly to this dual-action mechanism.
Lifestyle Factors
Mounjaro works best when combined with healthy lifestyle changes, including a balanced diet and regular physical activity. If these elements are missing, your results may be limited, even while on treatment.
Incorrect Dosage or Timing
Mounjaro is typically started at a lower dose and gradually increased. If you’re still on a lower dose, you may not yet be experiencing its full effects. Adjustments should always be made under medical supervision.
Underlying Medical Conditions
Certain health conditions, such as thyroid disorders, hormonal imbalances, or metabolic issues, can make losing weight more challenging, even with treatments like Mounjaro.
Unrealistic Expectations
It’s important to remember that Mounjaro isn’t an instant solution. Significant results usually take time, and steady, sustainable weight loss is healthier and more manageable long-term.
At Manchester Weight Loss Clinic, we can review your treatment plan, assess any underlying issues, and provide tailored guidance to help you get back on track.
Alternatives to Mounjaro
If Mounjaro isn’t giving you the results you were hoping for, there are several other medically approved weight loss injections available in the UK that could work better for your body and lifestyle.
Wegovy
Wegovy is another GLP-1 receptor agonist that works by regulating appetite and slowing digestion, helping you feel fuller for longer. Many patients who don’t respond well to Mounjaro may see better results with Wegovy, as it acts slightly differently on the body.
-
How It Works: Targets the GLP-1 hormone to control hunger and reduce calorie intake.
-
Effectiveness: In clinical trials, patients achieved an average weight loss of around 10% to 15% of their body weight.
-
Dosing: Once-weekly injection, similar to Mounjaro.
Saxenda
Saxenda has been widely used for several years and is another effective GLP-1 medication. While it requires daily injections rather than weekly, many patients respond well to this treatment.
-
How It Works: Mimics the GLP-1 hormone to regulate appetite and support gradual weight loss.
-
Effectiveness: Typically leads to a 5% to 10% reduction in body weight when combined with healthy lifestyle changes.
-
Best suited for: Patients who prefer slower, steady results or who haven’t responded to weekly treatments.
Orlistat
Unlike Mounjaro, Wegovy, and Saxenda, Orlistat works by reducing the amount of fat your body absorbs from food.
-
How It Works: Blocks around 25% of dietary fat from being absorbed into the body.
-
Effectiveness: Weight loss is typically more modest but can be effective when paired with dietary changes.
-
Best suited for: Patients who cannot use GLP-1 injections or who want a tablet-based alternative.
Tailored Support at Manchester Weight Loss Clinic
If you’re not losing weight on Mounjaro, it doesn’t mean your weight loss journey has to stop. At Manchester Weight Loss Clinic, we take a personalised approach to weight management, considering your health, goals, and lifestyle when recommending treatments.
Our expert team will:
-
Assess why Mounjaro may not be delivering the expected results
-
Recommend alternative medications or programmes that suit your needs
-
Provide tailored nutritional advice to maximise success
-
Offer ongoing support and regular check-ins to keep you on track
We believe successful weight loss isn’t just about finding the right medication — it’s about creating a comprehensive plan that works for you.
When to Seek Professional Advice
If you’ve been taking Mounjaro for several weeks or months and aren’t seeing results, it’s important to speak with a healthcare professional before making any changes. Increasing your dose without guidance or switching treatments on your own could be unsafe or ineffective.
At Manchester Weight Loss Clinic, we’ll work closely with you to evaluate your progress, discuss your concerns, and adjust your treatment plan where needed. Our goal is to help you achieve safe, sustainable results that improve your long-term health.
Achieve Lasting Results with Expert Support
Mounjaro has helped many people lose weight successfully, but it isn’t the right solution for everyone. If you’re not getting the results you expected, there are alternative weight loss injections and treatments that could work better for your body.
At Manchester Weight Loss Clinic, we’re here to guide you every step of the way with expert advice, tailored programmes, and ongoing support.
Book your consultation today and take the next step towards achieving your weight loss goals with a plan designed specifically for you.
This blog was written on behalf of Manchester Weight Loss Clinic by Pharmacy Mentor.